US Department of Interior Archives

US Department of Interior

September 18, 2023

Certain common chemicals associated with higher odds of cancer in women

By Carey Gillam

Women exposed to several widely used chemicals appear to face increased odds for ovarian and other certain types of cancers, including a doubling of odds for melanoma, according to new research funded by the US government.

Using data collected by the Centers for Disease Control and Prevention (CDC), a team of academic researchers found evidence that women diagnosed with some “hormonally-driven” cancers had exposures to certain per- and polyfluoroalkyl substances (PFAS), which are used in thousands of household and industrial products, including in stain- and heat-resistant items.

They found similar links between women diagnosed with cancer and high exposures to phenols, which are commonly used in food packaging, dyes and personal care products.

The study, published late Sunday in the Journal of Exposure Science and Environmental Epidemiology, did not find similar associations between the chemicals and cancer diagnoses in men.

PFAS chemicals, in particular, may disrupt hormone functions specific to women – a potential mechanism for increasing their odds of hormone-related cancers, the researchers determined. Hormonally active cancers are common and hard to cure, making deeper inquiry into potential environmental causes critical, the researchers said.

“People should care about this because we know that there is widespread human exposure to these chemicals and we have documented data on that,” said Max Aung, assistant professor of environmental health at USC Kreck School of Medicine and a senior author of the study.

“These chemicals can increase the risk of various different health outcomes and they can alter your biological pathways… that is important to know so that we can better prevent exposures and mitigate risks,” Aung said.

July 19, 2023

New worries about risks PFAS and other chemicals pose for pregnancies

By Carey Gillam
California researchers have found new evidence that several chemicals used in plastic production and a wide array of other industrial applications are commonly present in the blood of pregnant women, creating increased health risks for mothers and their babies.

The researchers said their findings add to a growing body of evidence showing that many chemicals people are routinely exposed to are leading to subtle but harmful changes in health.

“This is such an important issue,” said Tracey Woodruff, professor and director of the University of California San Francisco (UCSF) Program on Reproductive Health and the Environment. “It’s urgent we do more to understand the role that chemicals have in maternal conditions and health inequities. We are being exposed to hundreds of chemicals and this research contributes to better understanding the impact they are having on our health.”

Maternal death rates in the US doubled between 1999 and 2019, with mortality highest for African-American mothers.

In the government-funded study, which was published Wednesday in the Environmental Health Perspectives journal, a team led by Woodruff and other UCSF researchers said they found multiple harmful chemicals, including types of per- and polyfluoroalkyl substances (PFAS), in the blood of 302 pregnant study participants as well as in the umbilical cord blood of their babies.

At least 97% of the blood samples contained a type of PFAS known as PFOS, which has long been associated with multiple serious health problems, including birth defects.